To see the Video **** Please Click Here ****


Why People get MCS

A significant percentage of our population, due to their genetic makeup, are less tolerant to toxic chemicals. Most of them will develop MCS through exposure to toxic chemicals being used in our society.


What is Emf Sensitivity

Many people with MCS also develop electromagnetic field (emf) sensitivity due to permanent biological (cell) damage to central nervous system (cns) by toxic chemicals.


Can MCS and Emf Sensitivity be Treated

MCS and electromagnetic field (emf) sensitivity are caused by permanent biological (cell) damage to central nervous system (cns). In the case of MCS, the permanent damage is to certain brain cells of cns. Some organs of the body have the capacity to regenerate damaged cells, but not cns. For example, liver has a great capacity to regenerate and any damage to liver by toxic chemicals is recoverable. In the case of cns, the cell structure is very complex and usually regeneration of cells is not possible. Because cns cannot regenerate the damaged cells, any biological (cell) damage to cns is permanent. Only Gene Therapy has the potential to repair damage cells of organs, which can not regenerate cells. The findings of animal study on Gene Therapy to repair the damaged cells of cns are very encouraging. For more information read the article Gene therapy successfully reverses brain damage, by Anne Sarzin.

The damage to the brain due to stroke and the damage to the brain due to exposure to toxic chemicals have at least one thing common, short-term memory loss. It seems, in the case of the person with MCS, a portion of brain responsible for memory is damaged due to exposure to toxic chemicals. While in the case of the person suffered a stroke, same portion of the brain responsible for memory is also damaged, but damaged due to lack of blood flow to that part of the brain. At present, many Universities in US are conducting intense research on "Repair of Damaged Brain Cells for Stroke Victims." The early research findings are very encouraging. Similar research needs to be done on "Repair of Damaged Brain Cells for MCS Victims." The brain damage of a MCS victim is little bit more complex. Sooner we start doing research on "Repair of Damaged Brain Cells for MCS Victims"; sooner millions of MCS victims will receive some treatment and start to live like normal human beings.


CASE-CONTROL STUDY OF GENOTYPES IN MULTIPLE CHEMICAL SENSITIVITY

Background: Impaired metabolism of toxic chemicals is a postulated mechanism underlying multiple chemical sensitivity (MCS). Because genetic variation alters the rate of chemical metabolism, this study was designed to determine if MCS cases differed from controls for genetic polymorphisms in drug-metabolizing enzymes.

Methods: Female Caucasian participants (203 cases and 162 controls) were drawn from a larger case-control study based on a reproducible and validated case definition. Common polymorphisms for CYP2D6, NAT1, NAT2, PON1, and PON2 were genotyped.

Results: Comparing cases and controls, significant differences were found in genotype distributions for CYP2D6 (P = 0.02) and NAT2 (P = 0.03). Compared with the referent homozygous inactive (CYP2D6) or slow (NAT2) metabolizers, the odds for being CYP2D6 homozygous active (OR = 3.36, P = 0.01) and NAT2 rapid (OR = 4.14, P = 0.01) were significantly higher in cases than controls. The odds for being heterozygous for PON1-55 (OR = 2.05, P = 0.04) and PON1-192 (OR = 1.57, P = 0.04) were also significantly higher in cases.

Conclusions: A genetic predisposition for MCS may involve altered biotransformation of environmental chemicals. The CYP2D6 enzyme activates and inactivates toxins; the NAT2 enzyme bioactivates arylamines to protein-binding metabolites. A gene–gene interaction between CYP2D6 and NAT2 suggested that rapid metabolism for both enzymes may confer substantially elevated risk (OR = 18.7, P = 0.002). Our finding parallels others' observation of a link between PON1 heterozygosity and neurological symptoms in Gulf War syndrome. This first demonstration of genetic variation in drug-metabolizing enzymes in association with MCS requires replication. However, it suggests new research directions on genetically variable toxin pathways that might be important in MCS.
*** Read Full Story in PDF ***


Perfumes, Fragrance products and MCS

Most of the perfumes and fragrance products are made of synthetic chemicals. Some of the perfumes and fragrance products contain up to 600 chemicals including some toxic chemicals. Once a person gets MCS, his or her brain gets sensitized to chemicals and brain starts to react to practically any chemical. As perfumes and fragrance products contain multiple chemicals, due synergetic effect of some chemicals the reaction to the brain is magnified many times. This brain reaction usually followed by cardiac reaction and the person with MCS will start to feel very uncomfortable and sick. Perfumes and fragrance products made of natural products also contain chemicals, but not toxic chemicals. The chemicals in the perfume and fragrance products give the scent. As the brain of a person with MCS is sensitized to chemicals, most of the people with MCS will also react to perfumes and fragrance products made of natural products. People with MCS react to the chemicals in the perfumes and fragrance products, and practically all perfumes and fragrance products contain chemicals. People with MCS will react even more to some fragrance free products, because in some fragrance free products, the manufacturer usually adds additional chemicals to mask the fragrance. Fragrance free products are not necessarily chemical free products.

To see Single Photon Emission Computerized Tomography (SPECT) Scan of a MCS Patient's Brain: (SPECT) Scan of MCS Patient's Brain Before and After Challenge with Perfume Inhalation

Children's Health and Chemicals

Children are amongst the most vulnerable to the impacts of chemicals in the everyday environment. Children spend a large proportion of their childhood in childcare and at school where they can potentially come in contact with a wide range of chemical pollutants. Children's greater vulnerability to chemical pollutants.


We're Engulfed in Pesticides

The Centers for Disease Control and Prevention (CDC) began an ongoing study in 1999 in an effort to calculate the public's exposures to environmental contaminants, including mercury, tobacco smoke, and certain pesticides. By taking blood and urine samples, scientists can monitor the population's contact with chemicals present in the air, water, dust, food, and soil over time.

"So far, the results of the initial CDC National Report on Human Exposure to Environmental Chemicals confirm what many people already suspected," says Susan Kegley, staff scientist at Pesticide Action Network North America (PANNA). "The general population has contaminant levels exceeding those set by the Environmental Protection Agency (EPA) as safe." Read Full Story........


Creating Healthy Schools

As more people are becoming aware of the impacts of chemicals on health and the environment, attention is turning to some of the most vulnerable members of the community - children. Because children spend a large proportion of their childhood in childcare and at school, it is essential these environments are as free from toxic chemicals as possible.


Fresh Look at Food Preservatives

Unless you grow all your food in your own garden and prepare all your meals from scratch, it's almost impossible to eat food without preservatives added by manufacturers during processing. Without such preservatives, food safety problems would get out of hand, to say nothing of the grocery bills. Bread would get moldy, and salad oil would go rancid before it's used up. Read Full Story........


Genetically Engineered Food - A Serious Health Risk

Genetically engineered foods containing genes derived from bacteria and viruses are now starting to appear in the shops, and foods with insect, fish, and animal genes will soon follow. These genetic changes are radically different from those resulting from traditional methods of breeding. Yet, the sale of these foods is being permitted without proper assessment of the risks and without adequately informing the public, even though many scientists say that genetically modified foods could cause serious damage to health and the environment. Read Full Story........


Objectives of This Site

The main objectives of this site are to provide information about MCS and MCS related topics in a simple, clear and concise form. In the past people with MCS have been misinformed and mistreated. People with MCS should get all the facts, so that they can take care of themselves better. In the past many articles were written by authors with practically no experience with MCS which has mislead MCS community to certain extent. In some articles, people with MCS have been advised to take all kinds of complicated medical tests. A person, who knows what MCS really is, will never advise a person with MCS to take all these tests. These tests will not provide much benefit to a MCS patient rather than it will make his or her MCS much worse. In some articles, people with MCS talk about tolerating severe reactions. One thing they do not know that if they continue to tolerate severe reactions, their MCS will get worse. The foremost task for a person with MCS should be to slowdown the progression of MCS. For tips how to slowdown the progression of MCS read Twelve Golden Rules. This site will also provide information about Alternative Medicine and Gene Therapy. Alternative medicine will give very mild reaction to the treatment of common illness and it will not make person's MCS worse. While traditional medicine will give severe to life threatening reaction and it will make person's MCS worse. As far as treatment for MCS is concerned, I strongly recommend you to learn more about Gene Therapy and if possible, work with a Gene Therapy specialist.

Thank you for visiting MCS Homepage. If you like MCS Homepage, please tell your MCS friends about this site. Please also send your comments and suggestions.

Disclaimer: MCS Homepage provides only information about Multiple Chemical Sensitivity (MCS). The information provided in this website should not be construed as offering medical or legal advice, which should be obtained from qualified professionals. MCS Homepage disclaims any liability for any claims made based on information posted at this website or any other site to which it is linked. We verify posted information to the best of our abilities but cannot be held responsible for omissions or subsequent changes.

MCS Homepage ã Copyright 2000